my dad is refusing to take vaccines because he thinks taking it will automatically make him vote dem because of nano-machine in them.
he also thinks vaccines are kind of HRT.
anyways how’s your day?
I hope you are an adult and no longer live with your parents.
If that is the case remember this. If you cannot have pleasant encounters with him, you are under no obligation to have them at all.
No obligation to keep seeing them, would be kind of hard not to have parents 😛
You still have them, you just don’t have contact with them.
but then who will take care of them? they were there at my time of need, shouldn’t i also be there?
You sound like you have a good relationship with your parents, many don’t.
You can be there for them when they need you without putting up with the anti-vax ravings you mentioned. It is called setting boundaries.
You do what you think is right but also understand that is not a universal thing for all people.
You sound like you have a good relationship with your parents
not really.
i think it is best to minimize contact but not keep null, since these kind of people are self destructive.
that’s the only reason i stayed , for their health issues.
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Nope they chose to get a child. You dont have to Do anything for them.
The “them” in that sentence refers to “encounters” not “parents”.
Ah so that explains my D cups
RIP your inbox.
I’ll show my man boobs to anyone who wants to see them. Usually people tell me to stop showing them and say things like “gross” and call me bear tits but that hasn’t stopped me from whipping them out on every occasion and non occasion
Block his router of the content
I watched birds are not real Ted talk the other day, I think it was awesome to give a perspective on the conspiracy stuff and how people run with it.
If it flies, it spies. 🐣
Sorry you are going through that. Same thing happened to me, it really sucks :(
you should introduce him to the library
Gives a whole new meaning to the term “parental controls.”
While I’m sure there is a crazy markup, it’s important to note the cost to produce - as in manufacture - does not include the cost of drug discovery, which is extremely expensive and involves a good amount of risk over a long period of time.
You can’t just compare the cost of discovering a new drug vs. cost of producing a generic without any research like that.
Last year, the three largest US-listed pharmaceutical companies by revenues, Pfizer, Johnson & Johnson, and Merck, spent a combined $39.6 billion on R&D. That is, admittedly, a lot of money. But less than Medicare is currently paying on just ten drugs
While Big Pharma holds vast portfolios of existing patents for prescription drugs, the innovation pipeline for new drugs actually has very little to do with Big Pharma. In reality, public sources — especially the NIH — fund the basic research that makes scientific breakthroughs. Then small, boutique biotech and pharmaceutical firms take that publicly generated knowledge and do the final stages of research, like running clinical trials, that get the drugs to market. The share of small companies in the supply of new drugs is huge, and it’s still growing. Fully two-thirds of new drugs now come from these small companies, up from one-third twenty years ago. It is not the research labs of Pfizer that are developing new drugs.
Pfizer COVID vaccine wasn’t researched or developed by them. It was developed by the German BioNTech.
Still, bringing it to market at the required volumes requires extreme amounts of capital, there’s a reason no one can enter the club.
I like Lemmy for exactly this - whenever someone incorrect makes a statement they’re factchecked.
Thank you kind person for finding and sharing that source.
OP didn’t make an incorrect statement though. What they stated was an important part of the equation. I think a lot of people don’t take that type of thing into account and they will read what this post says and assume that Pfizer should be charging $13, or maybe something pretty close like 15 or 20. Clearly 1400 is far far too high, 13 is too low. A reasonable price allows the manufacturer to be successful while not gouging consumers lies somewhere in between, but much much closer to the low end than the high. To me that’s really what the person you are responding to is giving evidence for.
Thank you, this is exactly my point.
That’s just an excuse because many drugs are sold at prices much lower what they are sold in the US. They are not selling them at loss in other countries.
Definitely not at a loss to produce no, but maybe a loss overall.
My bet is that the US subsidizes R&D by paying obscene amounts for the drugs and the EU and others just serve as extra income
Your bet?
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That’s what they make you believe. Why American still pay high prices for insulin? It doesn’t cost that much to produce. It just those companies are paying politicians to keep things in their advantages and give you those excuses.
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Paxlovid is not a COVID vaccine, it’s an antiviral.
Smh just use windows defender people
Well here you go again when people with no scientific education pull up literature as a gotcha. Thanks for giving me flashbacks to the high times of the pandemic. Sorry for the harsh reply but its posts like this that just funnel into misinformation around this already heavily polarized topic.
To explain, Paxlovid is not a vaccine, it is an actual medicine/treatment. So it was not funded by taxpayers as the article states. Unless there is some other info on how this specific medicine was also funded by taxpayers of course, I am not an expert on research funding. But the article only mentions vaccine research.
That said, I also do not think its a fair price necessarily. But it is true one should not equate production price as a fair price as R&D of drugs have high costs, mostly also because a lot of drug programs fail, making all prior investment to them a loss.
Fuck off with the big pharma apologetics.
Boo hoo the corporation got millions in taxpayer money to develop a vaccine and now they have to profit off of it. I feel so bad for them.
This is subtle astroturfing.
Guess this comment of mine will also get deleted but here goes nothing.
The article is about antiviral medicine, not a vaccine. So you are getting angry at the wrong thing.
Are we talking about the vaccine here? Sounds like a post-exposure drug to me
I don’t think it takes 1.4k to move anything anywhere.
Yes we can. It’s just doesn’t give a good faith assessment of the situation. And why would I want to do that if it’s counter to my rigid world view? sigh better add an /s
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Torches would burn the bodies too much. You need a proper grill.
changes need to happen badly
Sounds good. In the meantime, I’m going to buy some Pfizer stock for my kids sake.
This comment is loaded with wishful thinking.
That’s optimistic tbh. More like my comment is the result of 2 decades of fighting the good fight only to watch those I’m trying to help dig a deeper hole. Time to tend my little patch of grass, build a sturdy fence, and hope for a renaissance.
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There is some level of R&D they do to productize it, manufacturability and scaling. And running drug safety trials cannot be cheap, especially the liability insurance.
That all said, I think it’s criminal that the university labs pay so little. PhD students barely make over $40k, set by the NIH. Not adjusted for CoL either.
I think I have more of an issue with the for-profit nature of pharma companies. Shareholders shouldn’t be involved in medicine.
The woman who got the nobel prize for the mRNA research that led to the Pfizer vaccine did a lot of it while employed at Pennsylvania University before they fired her because they didn’t see the research leading to making them money. Then she moved on to Biontech where she continued the research.
I’m not sure how much was done at the university but it was probably not insignificant and then biontech got lucky and snapped it up for basically free.
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I’m always curious about the actual numbers. Here’s their R&D budget by year:
And their overall revenue:
In 2020, their revenue was about $40B on $8.5B in R&D cost. They had a huge revenue increase the last few years, with 2022 being $100B, but R&D only increased to about $11B.
So they do have R&D, but it’s not that big compared to the money they’re bringing in. Their net income has increased substantially, as well.
Thank you for finding the numbers
In the bio industries R&D has almost exclusively become just the D. We like to think that there are a bunch of scientists doing lifelong, painstaking research to develop new drugs or treatments within the labs at Pfizer, Merk, Lilly, or whatever, but a significant portion of the research is done at small independent or school funded labs.
Once one of those small labs creates a decent treatment that will likely pass government testing, a large corp will buy it and say “We just made this brand new thing!”. Really though, their R&D budget is spent on acquisition, production, supply chain development, and marketing.
Working in R&D in a few different positions in my career and this is absolutely the case. Hell some of them you could equate to white label SaaS products. Using research from universities putting it in a neat package and selling it.
The corporate bio industry is so fucked up I can’t even begin to describe it. I tell my friends and family stories, but I sound like an insane person to them. The scale at which money is thrown around is just too large for most people to imagine.
Like this: imagine a worker that makes less than $35k per year processes, and is soley responsible for $20M in products, per month. Product that people all around the world not only use, but ingest. Now imagine that that one worker is the only one in the world who knows how that product is processed. That’s how bio manufacturers work.
In addition to that, I’ve heard that a large portion of that R&D spending is on iterating drugs they already own so that when the patent runs out they can patent a new version and lobby the old one to be made obsolete so generics can’t be made.
Who wants unpaid internships!
AFAIK some US agency did R&D for COVID, they just
bribedsponsored Right People
Didn’t the government fund the development? So… it’s not like they need so much to recover R&D right?
Welcome to the United States. Everything is subsidized, then turned around to fuck the average person.
The government did not for Pfizer. That was Moderns. Pfizer did spend billions of their own cash. This move is largely because the executive leadership way overestimated the amount of covid vaccine and drug treatment revenue for this year, and they are desperate to make up ground.
So they are raising prices and cutting across the board rather than admitting they didn’t know what they were doing in their projections. CEO isn’t taking a pay cut though. Morons got a winning lottery ticket in the pandemic and assumed they’d keep winning every year.
That is almost always the case. Pharma companies are mostly just advertising firms
I’m fine with the public-private partnership but money like this needs to come with strings attached. We should’ve made an agreement to cap the price. We developed these drugs under the Trump administration so I really don’t think the impact to poor and middle class citizens has ever been a thought in his mind.
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Much better strategy: you take the medicine… survive… and refuse to pay in protest. Sure, you might get sued for non-payment of bills… then a bunch of people can fight a class action lawsuit against pfizer.
I get the anger. We really need to fully socialize these medical development centers. But on the other hand, they did most of the work. They didn’t have to.
I’m sure the research was publicly funded, and the profit will be private as is tradition.
Yep, that Pfizer for you, using taxpayer money to R&D drugs they will use to price gouge the public who paid for it, out of the kindness of their hearts.
They didn’t do most of the work. Not even close.
So many Martin Shkrelis out there pricing drugs to the highest level they can get away with. Every big pharmaceutical company does this kind of thing, especially with new drugs.
Seriously, people are acting like this is new. There is no sense in shaming them we’ve had it brought to the mainstream by people like Martin Skhreli and nothing has been done. Martin Skhreli himself is only in jail because of his ponzi schemes, a.k.a. screwing other rich people out of their money. The only reason Pfizer was praised was because it was needed in a time of need and because they hired plenty of lobbyists.
Ive accepted this behavior as typical and standard issue human nature.
That is why i am mot having kids, seeing that extinction is the best future for humans. Evolution puts any other intelligence in the universe at risk.
It’s been too long since the aristocrats were reminded that they need us more than we need them and that they can’t hire enough of us to stop the rest of us once we take an idea to mind.
13$ to produce including all the R&D behind it?
I’m not a fan of big pharma, quite the contrary, but I’d be curious to know where this number comes from…
As if they’ll lower the price once they’ve recouped the R&D costs ten times over.
Who paid for the R&D?
That would be the us government soooo… The citizens of the usa
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Don’t ever think for a second that pharmaceutical companies did anything during Covid for our benefit. They were working their actuarial tables to figure out how they maximize their profits in the future against sick people dying.
And who is in charge of making sure this kind of immoral illegal thing doesn’t happen? People who are still somehow allowed to collect kickbacks in exchange for looking the other way.
Ok who let Martin shkreli out of jail?
I think he was released last year.
Explain why we make it legal for companies to set their own prices again
It does make companies more willing to invest more into drug research , which is a good thing.
Drug research is overwhelmingly publicly funded. Private R&D is a PR myth we were fed to justify high prices.
I never said wasn’t. What I said is still true.
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No. Those two statements don’t go together like that. They aren’t making big new drugs. At most they are looking for ways to adjust the formula so they can extend patents. There is no amount of profit that makes them willing to do more R&D.
Covid treatment was publicly funded. This is a case of public funding going to research and private companies profiting from it.
Everyone should be outraged from the situation. This cheap treatment is being denied to the majority of the world’s population because of patients, and so covid has more opportunities to mutate and make everyone less safe.
Why don’t we just take investor money and invest in it ourselves?
Others have already pointed out that the covid vaccine was publicly funded ergo the benefit should be publicly owned
That’s called freedom! Go to Russia if you don’t like it! /s
Literally
