• GreatWhiteBuffalo41@slrpnk.net
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    2 months ago

    Never. Turns out my issue was undiagnosed ADHD and trauma. Therapy and adderall have done wonders for me. I was trying to treat depression by itself, not as a side effect of another issue.

  • nondescripthandle@lemmy.dbzer0.com
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    2 months ago

    Define ‘working’ becsuse a lot of strife can come from the differences between what you’re expecting it to do and what will actually happen. For me, it just made it easier for me to lift myself out of bed in the morning and that’s about where the progress ends. And that’s the one I found after years of trying ones that were worse. They’re not happy pills, they just let you deal with the horrible shit instead of becoming immobilized by it.

  • mika_mika@lemmy.world
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    2 months ago

    Months. It took months of my med schedule before I was like “maybe these are working”. My motivation and functioning was like zero still, but I wasn’t depressed anymore.

    Then doc put me back on a stimulant and it was so much more drastic an improvement I was frustrated we didn’t do that first.

  • AndyMFK@lemmy.dbzer0.com
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    2 months ago

    They never worked. For some unlucky people, anti-depressants just straight up don’t work. If you’re new at it, keep at it, but if it’s been a few months it might be time to switch medication. if you’ve already switched a bunch of times, they might not work for you and your only option is probably therapy

      • Seems to only mention SSRI specifically, not about antidepressants in general

        Also this: “suggested that the active ingredients in 10 of the most popularly prescribed antidepressant medications made a meaningful difference in only 15 percent of the patients who took them, almost always in those patients suffering from the most severe depression

        So yeah… that’s me lmfao…

    • neaptide@lemmy.world
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      2 months ago

      There actually are other options for treatment-resistant depression, which is defined as depression that has little or no response to standard treatments like antidepressants.

      • Transcranial magnetic stimulation (TMS): uses magnetic currents to stimulate the brain while awake, typically provided 5x per week for 6 weeks (although there are now newer protocols that are much shorter in duration)
      • Ketamine: a general anesthetic drug typically provided via a nose spray 1-2 times per week for 8 weeks
      • Electroconvulsive therapy (ECT): uses electricity to induce a small seizure in the brain under sedation, typically provided 2-3 times per week for 3-4 weeks

      Source: https://www.mayoclinic.org/diseases-conditions/depression/in-depth/treatment-resistant-depression/art-20044324

      I try to spread the word about these treatments when I can because TMS helped me immensely after trying just about every antidepressant out there with no luck.

  • silspd@lemmy.world
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    2 months ago

    Escitalopram took only one day for me. For both anxiety and depression.

    Bupropion took 3-4 weeks. For depression.

    Trintellix took about 2 weeks. For anxiety.

  • Xaphanos@lemmy.world
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    2 months ago

    Depression. Sertraline/Zoloft. Months.

    Initially, it helped a small amount. Possibly placebo. It was well-tolerated, so the dose was doubled. Then months (maybe 3?) of slight improvement.

    But when it really took hold it felt sudden.

  • zlatiah@lemmy.world
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    2 months ago

    Depression, Prozac. Approximately 2-3 weeks when the initial benefits kick in, which is also how long it roughly took for me to feel depressed again when I once accidentally stopped the medication

  • FRYD@sh.itjust.works
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    2 months ago

    I’ve taken a bunch of anxiety meds. The only one that worked somewhat was Ativan, but I stopped after a few weeks because I was too anxious about taking it regularly and developing a benzo addiction.

  • FollyDolly@lemmy.world
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    2 months ago

    Zoloft, it took three days to start working. It had been an absolute gamechanger for my anxiety and I love it. 10/10

  • SaveTheTuaHawk@lemmy.ca
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    2 months ago

    A lot of those FDA approved drugs have been proven to do nothing, or far less than therapies.