• Amicese
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    1 year ago

    Typical antidepressants are meant to manipulate serotonine levels. However, there is to this day not one study that clearly shows that there is a connection between serotonine levels and depression.

    Serotonin levels in the brain respond to antidepressants.[1]

    Yeah, because Psychiatrists are allowed to lie about the phenomena of the brain.

    Those pills, however, really make you complacent. Many people report “feeling less” and being “emotionally numb” after taking them.

    Yep. They also cause health problems.

    Right now, even primary care physicians are giving these pills out like candy. So many people take these pills. Ridiculous numbers from the UK: 17% are taking antidepressants, and 13% are on opioid pain prescriptions. That is absolutely mind boggling.

    It’s straight up fraud by the rich drug capitalists.

    The rise in ADHD drugs also occurred during the War on Drugs. Meth and Weed use by the oppressed are punished by the rich, yet they turn around and promote it to children. It comes off like cultural appropriation.

    I only ever took plant based antidepressants, and the older I get, the more happy I am about that decision. Before anyone wants to say that those can’t work: They were tested to be almost equally effective, but without the side effects. And I wasn’t getting numb or anything, and I still have my libido.

    Do you have a resource on the testing they did?


    1. Andrews, Paul W., Aadil Bharwani, Kyuwon R. Lee, Molly Fox, and J. Anderson Thomson Jr. “Is Serotonin an Upper or a Downer? The Evolution of the Serotonergic System and Its Role in Depression and the Antidepressant Response.” Neuroscience & Biobehavioral Reviews 51 (April 2015): 164–88. doi:10.1016/j.neubiorev.2015.01.018. ↩︎

    • @Stoned_Ape@lemmy.ml
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      21 year ago

      Do you have a resource on the testing they did?

      It was a German meta study of I believe 12 studies where placebo was tested against both synthetic ADs and St. Johns Wort (which is what I take). That was 13 years ago. I try to see what I can find.

      • lemmyreader
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        11 year ago

        Interesting that you mention St.Johns Wort, it is something which I used from time to time, and I like that it is natural with minimal side effects. (I’ve been told that women should be very careful with this as it conflict with some contraceptives).

        • @Stoned_Ape@lemmy.ml
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          21 year ago

          St. Johns Wort generally changes the outcome of dosage of medications. A lot of stuff should be taken in different doses. Pill contraceptives are reduced in efficacy by St. Johns Wort, and that can mean that the protection is lowered.

      • Amicese
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        11 year ago

        It was a German meta study of I believe 12 studies where placebo was tested against both synthetic ADs and St. Johns Wort (which is what I take). That was 13 years ago. I try to see what I can find.

        Thanks, I’ll read that study if you find it.

        • @Stoned_Ape@lemmy.ml
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          11 year ago

          I think it was this one: https://www.cochranelibrary.com/cdsr/doi/10.1002/14651858.CD000448.pub3/full

          You can find the full text here (Click on the blue buttons [Libgen] to download): https://libgen.li/edition.php?id=36416454

          Very interesting bit: “Both in placebo‐controlled trials and in comparisons with standard antidepressants, trials from German‐speaking countries reported findings more favourable to hypericum.”

          That’s odd. I wonder what the reason might be.

          Trying to ping the user @lemmyreader@lemmy.ml Please tell me if that worked. :)

          • lemmyreader
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            1 year ago

            Thanks for sharing the web links.

            Trying to ping the user @lemmyreader@lemmy.ml Please tell me if that worked. :)

            Worked :) And let’s ping in the original question poster as well @Amicchan@lemmy.ml just in case.

            Hypericum (St. John’s Wort) pills can be bought in some regular shops here in Europe. I have a tendency to use them in the Winter, but this time it didn’t go so well. I also have it as tea, maybe I’ll give that a try again when needed. Luckily I found other ways to feel better. Odd thing about the results for German speaking countries.

            Trials from German-speaking countries reported more positive findings than trials from other countries (RR = 1.78; 95%CI 1.42 to 2.25 vs.1.07; 95% CI 0.88 to 1.31, respectively; see comparison 1.5 and Figure 2).

            What do these numbers mean exactly ? Was it a huge difference or not so much ?