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Joined 2 years ago
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Cake day: July 2nd, 2023

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  • So I’m a physician and I support most things people do to import their health but I do try to make sure they’re fully informed. In terms of fasting, this cohort study found an adverse association between fasting and cardiovascular death. There are limitations to the study (self-reported diet, etc.) but it followed 20,000 people for 8yrs which is pretty good. Definitely need more study in this area, especially considering the complexity of human metabolism. Here’s the highlights from the study but the full text is available at that link:

    • People who followed a pattern of eating all of their food across less than 8 hours per day had a 91% higher risk of death due to cardiovascular disease.
    • The increased risk of cardiovascular death was also seen in people living with heart disease or cancer.
    • Among people with existing cardiovascular disease, an eating duration of no less than 8 but less than 10 hours per day was also associated with a 66% higher risk of death from heart disease or stroke.
    • Time-restricted eating did not reduce the overall risk of death from any cause. An eating duration of more than 16 hours per day was associated with a lower risk of cancer mortality among people with cancer.









  • It’s not that CPR doesn’t work, it’s that outcomes after resuscitation usually aren’t great. The study doesn’t disclose ages or neurological outcomes post-rescuscitation so that limits my interpretation but quick rescue and quick CPR is key in those acute, single reason emergencies. That isn’t to say in an emergency situation you shouldn’t try especially since you don’t know that person’s wishes. There are good outcomes but usually for underlying healthy people who had one thing go wrong. Think the athlete who’s heart stops on the field for some reason.

    I’ve admitted at least a thousand people into a hospital through the ER and I tell everyone that it’s not like on TV. If you’re older, sick, multiple chronic diseases, don’t take care of yourself, etc. the chances of any kind of quality of life after CPR is limited. Death is terrifying and I understand them wanting to try but it’s just not realistic a lot of the time. We need better deaths in the US and more in-depth end-of-life conversations with our patients. That should be starting in the PCP’s office. Trying to discuss that with a patient in the ER who’s already scared isn’t ideal. I’ve seen patients with do not resuscitate/do not intubate orders on file change their mind when they’re suffocating and panicking then once they’re more stable immediately change their mind back.


  • Thanks, that looks legit, especially considering they got a Nobel for the process. Red blood cells wouldn’t work though, no genetic material to tell the cell what to do. Skin cells sure but deeper layers before they ditch their nucleus. The bottom layer of your epidermis is already made of stem cells that continuously produce new keratinocytes (skin cells). That’d make sense as a starting point for what they did. I’ve been in medicine for seven years and there have been all kinds of crazy claims made but researchers so I’m always skeptical.




  • Couple of things it could be:

    1. You locked your knees without realizing it, shut down the blood return from your legs, then had a drop in blood pressure due to decreased blood return to your heart causing you to pass out.
    2. You took a big hit, expanded your chest, held it, decreased blood flow through your thoracic cavity due to the increased intrathoracic pressure then a blood pressure drop as above.
    3. Your vasovagaled yourself somehow (bearing down on a held hit maybe or just due to weed effects) which is increased parasympathetic nervous system tone that drops blood pressure
    4. Some weird shit 🤷🏼‍♂️, the body can be odd and changes as we age so maybe you just can’t smoke weed now cause of the earlier mentioned weird shit

    I agree with your doc (I’m a family med physician), don’t smoke if all of a sudden you’re passing out.