In 1973 a reportedly drunk driver flattened a tree in the middle of the Sahara, which sounds unremarkable until you learn it was the only tree for 250 miles around, a 300-year-old acacia so isolated it was marked on maps covering half a continent. https://share.google/ePM21R48Aq0VRqTUb
Would need a pretty good fence around it. Sounds like unaware and drunk drivers are great at hitting the only thing around for miles.