Glucagon-like peptide-1 agonism - GLP-1, common in obesity medicines - is not essential to weight management, according to preclinical research led by Richard DiMarchi and Matthias Tschöp, with funding from their startup company Bluewater Biosciences.
walking and biking for evertday errands make a big impact too.
I actually made a comment addressing the car-centric layouts (and how it is basically impossible to walk anywhere in many parts of America) elsewhere in the thread here.
To expand on that commuting via public transit often requires you to walk between house and transit, between stops, and to your destination. I log 1 mile each way each day or around 10 miles a week.