Now consider that Scripps Research, who is developing this, is US-based and receives a lot of federal government funding, and that Trump/Musk/DOGE have been slashing and burning all kinds of federal science staffing and funding. Also consider that their main federal funding comes from HHS, which RFK Jr., notorious vaccine hater, heads.
Then weep. Progress on this may be stalled for a long time.
Maybe, or maybe some other country poaches them.
True, that could also happen, but I wonder how transferable this type of research project is. Does the research lead actually own it and can take it with him or her to a new place, or does Scripps own it? I don’t know the answer.
Flash drive or cloud transfer when you flee the country, the modern replacement for briefcases full of blueprints.
It’s not an question of if, it’s a when thing at this point. Just like we happily scooped up talent fleeing the Nazis, someone is going to make it easy for highly skilled US citizens to bail. Probably Europe, since they seem to be stepping up to the plate in a lot of ways.
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Keep me updated on which countries approve its use so I can add them to my travel plans.
Make sure they’re also countries that will give vaccines to foreigners. I had a hell of a time getting routine flu shots in Spain, Hungary and Thailand. The systems are often set up with the assumption that you’re a citizen or have a national healthcare ID of some sort. Without that, good luck finding a clinic who will give you a shot.
india and thailand caters to medical tourism, i asusme alot will be either going to canada(maybe) or asia.
Not really a valid assumption. Most vaccines are not available at tourist clinics, though maybe they should be, seems like the demand is increasing.
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Think about all the capitalist profit businesses make for common cold symptoms alone, with over the counter meds and stuff.
No way something like this would be allowed in our current society.
Just an interesting thing to share… I lived in the US until I was 40 and moved to Norway. They just don’t sell “cold remedy” meds here, or at least not even close to the extent the US does. We have sore throat drops, and OTC pain relief. Some cough medicine but it’s pretty weak imo. I suspect this is because the expectation here is that if you’re sick, you take sick time off work. You can rest and recover. Going to the doc to get sick time approved is at most like $20 and if you and your doc have a good relationship, you can do this via email. In the US, you’re expected to power through unless contagious and even then, just try to pretend you’re okay.
What you’re saying hits home.
Conservatives have this tough guy routine, that going to work when you’re sick is just manly or “alpha”. It’s bullshit. Then they spread it so everyone else can get it.
But the tough thing to do, is go to work, after pumping yourself full of nyquil, or Tylenol, or whatever. It’s just so stupid and obvious. They’re so “tough” yet they need all this OTC junk to ease the symptoms. Not to mention, not being productive at work, cause you feel like shit. As well as taking longer to get better.
Personally, I prefer not to take any meds at all. Just go home, sleep a lot, drink water, eat soup, chill, rest, etc.
I just got over being sick for 2 weeks and even though I was lucky enough to have that much sick time, I absolutely wanted the strongest meds I could get because I was miserable.
you’re expected to power through unless contagious
No, you’re expected to power through and they don’t give a fuck whether you’re contagious or not.
dextrotomorphan, is the cough medicine, i find it has little effect on coughs. i believes its the 1st generations(diphenhydramine, doxylamine,bropheneramine,etc) anti-histamine that is preventing the smptoms, because also prevents mucus production via anti-cholingernic effects and the cough, besides the fever.
and pehnyleprine has no effect on you what so ever, you need the pseudoephedrine, but its regulated in the usa, and only available at the pharmacy counter, because Pseudoephedrine is used to make METH. dextromorphan is also recently been regulated, requiring ID, because stupid young children teens, are robotripping on it apparently.
However, I’d expect businesses would also want to reduce cold and covid’s impact on employee productivity? Wouldn’t fewer employees needing to take sick time because of cold/covid increase their profits? Outside of businesses that profit from cold/covid, I don’t see what the motivation for businesses would be against this vaccination.
Agreed, but you could spin it a number of ways. The “tough guy work ethic” cultural propaganda is to just go to work when sick. The fact that your not as productive when you feel shitty, well, the owners would have to actually care. Their argument is they’d probably prefer a sick employee only working at 70% their normal productivity, is better than letting them stay home.
The other much bigger thing is, how much money is over the counter meds industry profiting? Do they have lawyers and lobbyists? Is this profit entrenched in Wall Street investors and quarterly profits?
Which wins? Altruism for the worker bee, or rich peoples money and power?
But does that outweigh the amount of days lost from people taking sick days?
Oh sorry America. The civilised world would be making that calculation though.
Vaccine tourism will become a thing.
Knowing the current administration, it will end up just like abortion tourism… but instead of only being persecuted in red states, it will be federally outlawed.
medical tourism to places like india, thailand,etc for dental and medical treatment.
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Yeah, but if you’re a certain shade of brown, you might not make it back in.
Or gay, or have voiced opposition to the Trump administration: https://www.theguardian.com/us-news/2025/mar/18/germany-investigates-after-national-with-green-card-arrested-at-us-border
We’ve got a lot of Americans who want everything tested for 20 years to make sure your eyes don’t fall out after a decade.
Meanwhile, in the U.S. I’m sitting here wondering if we’ll even have a flu shot available for next winter, let alone a new vaccine that can protect from Covid and the common cold.
I know my state would find a way to ban this shit. They hate anything that prevents needless suffering.
*country
The EU will welcome your scientists and Pharma companies with open arms.
They still won’t take it.
Who gives a shit? I will take it as will my entire family.
Herd immunity and whatnot
Necessary to protect people with weak immune systems, certainly. But we rarely get better than 60% of the population flu vaxed. It is still vital to deter higher instances of hospitalization and to blunt the rate of spread.
You realize if the morons die out everyone else remaining still has heerd immunity, right?
Selection bias. All the survivors will say “See! We didn’t need the Fauchi Ouchie!” while all the dead won’t say anything.
I’ve straight up been at an event where a speaker asked “Raise your hand if you’ve died because you didn’t get vaccinated! Nobody? That’s what I thought.”
Yes, but we’re slowly evolving away the dumbest and most dangerous of the population.
In the past we sent them running eagerly into the meat grinder of war.
Now they’re building up like cord wood, and starting to smolder.
we’re slowly evolving away the dumbest and most dangerous of the population
Do you believe that exposure to misinformation is a consequence of genetics? Like, people are just born with an ear uniquely tuned to anti-vax radio, television, and social media?
Now they’re building up like cord wood, and starting to smolder.
“RFK Jr is getting his eugenics backwards” is one hell of a take.
I believe vulnerability to misinformation is an effect of genetics, and this puts pressure on those genes to go extinct as they are not suited for survival.
There are people who have genuine medical reasons to not take vaccines (e.g. an allergy to a common ingredient) or who are so immunocompromised that a vaccine won’t keep them alive, and they rely on other people getting vaccinated to avoid dying. It’s not just antivaxers who antivaxers kill.
it’s not just antivaxers who antivaxers kill.
Reminded of the family whose kid died of measles saying “Our other kids survived, so it was fine”.
That young child wasn’t the one who had been deluded with misinformation.
In the '80s, Reagan thought that AIDS was killing the right people.
Now it’s the other way around.
AIDS thinks Reagan is killing the right people?
Doesn’t matter, they ll die by measels before anyway
They can die from it alone in their house. Stop going to the hospitals and infecting infants and newborns that can’t get it.
I wonder how this could help those with long COVID.
long covid, aka sequelae (medical term) means you had a long last complication that seperate from the virus. the inflammation couldve damaged parts of your body you are chronically suffering from. it might not help, since its not caused by the virus anymore.
its basically like having PHN, or nerve damage after shingles, the vaccine wont help you with that.
I don’t think it’s going to help them. long covid is past the stage of virus infection. It’s where the body is attacking itself.
Doesn’t chickenpox turn into shingles by infecting the nervous system?
Could long covid be related to that?
The virus that causes chicken pox, lies dormant in your nervous system, where your immune system can’t get it, for decades. Then much later in life the virus can reactivate, infect along those nerves, causing shingles.
This is the important part of the chicken pox vaccination the we don’t talk about nearly enough.
- If you get chicken pox, you’ll probably be ok (although not everyone is) and get over it, becoming immune. But the virus will still lurk, opening you to shingles attacks when you’re much older
- if you get the vaccination, you’ll probably not only not get chicken pox, but will also not get shingles
Supposedly something like one in three elderly will get shingles, when they can’t as easily deal with it. As current generation gets old, that illness will practically disappear
We can save shingles if we stop vaccinating now!
If you have older relatives and friends (50+), do remind them that we have shingles vaccine: Shingrix.
And let them know it hurts for a few days, so get it on a Friday.
Nah don’t fuck up your weekend, call in sick as needed if you’re working.
This is a good point. I do tend to get my vaccine shots (Covid and flu) on Fridays to account for recovery days.
the varicella vaccine prevents severe infections, but its not entirely protective against it, it just makes you asymptomatic, and once you get reinfected it can still become dormant, and get hsingles, just less chances of getting it.
different issues. varicella can cause shingles, when it travels to your dorsal root ganglia near your spine or the ganglia in your head,or rarely it can become dormant in your autonomic nervous system.
varicella, a herpes isnt the same thing as coronavirus. long covid is just laymen terms for complications or sequalae. Covid can trigger shingles, because your immune system is fighting the covid virus instead of shingles.
Many long COVID infections are causing/caused significant damage to organs (https://pmc.ncbi.nlm.nih.gov/articles/PMC11834749/). A vaccination isn’t going to reverse organ damage.
So I’ve read up a good bit on this topic / issue. Many times long covid can be a result of the infection causing neural damage which then leads to long term inflammation. While this isn’t the only reason for it, doing a protocol to repair damaged neural tissue and receptors has been effective with people I know. It has reduced or removed the symptoms they experience.
Took me over half a year to get over covid.last time. I coughed so.much and so hard for so long I got a hernia.
They researching for quite a while now. I really hope this will get to the market. Another bonus is, that it theoretically doesn’t need to be rushed.
But the antivaccines movement will totally Lose it.
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OK, so if I understand this correctly, they don’t train the immune system to target these sugars, since they’re used by human cells. Instead, they remove them during the vaccine administration so the immune system can train on the bare spike protein. Cool. Now how would this help when new virus copies come in with sugar-coated proteins, some time after the sugar stripping agent is gone from the system?
Yeah I also don’t understand this part. Can the antibodies targeting the bare spike protein attach to it despite the presence of the sugars? Or are there a few spike proteins in the virus which do not have the sugars, not enough to effectively develop antibodies but enough for already existing antibodies to attach to?
I may have missed it in the article, I’m not in life sciences so I don’t have all the prerequisite knowledge for this
Edit: this came out sounding super negative, I’m actually super excited about this development and all I want is to understand a bit better how it works
Yes same, I see they’ve gotten a positive result so I assume there’s a process, I just don’t understand it.
from what ive gathered from the abstract,t he glycosolation prevents a more robust immune response, less antibody titers, when they removed it they noticed the immune system recognizes the spike proteins more easily so a stronger immune response and more antibody produced, and a longer titre of antibodies.
first when they removed the “glycans” it revealed more of the protein of the virus, so the immune system recognizes different parts or more of it, so stronger and longer last immune response. the conserved parts is the parts of the proteins that dont mutate much so its easier to become immune to it, the sugars originally hid that part.
Coronaviruses are not the only cause for what is considered the “common cold”. I remember that some Rhinoviruses, Adenoviruses and I think a forth family of viruses also cause symptoms that are counted as a cold. It’s kind of a catch all term.
Okay, sure. Then a third of all colds, which feels like a good start.
Sure, I’m not opposed either! Just want to make sure people here have the information needed to not be disappointed later.
This I want.
Tha’s a new thing for me.
I wish they had detailed how the removal of glycans is accomplished. Alas, Wikipedia doesn’t even have an article about “glycoengieering”, which would likely be the term for this method.
Edit: oh, I also mistunderstood. I started thinking that it accomplishes removal of glycans from the invading virus, but instead it’s only removal of glycans from the vaccine, exposing more of the virus, leading to more diverse antibodies. Which is far more doable, and not a big technical novelty. But apparently, quite useful. :)
Hah; I can hear RFK jr already.
[Gravely voice] “Look if you want to put that unproven poison in your body I would not recommend doing when alternatives exist, like oranges, and Vitamin D, and death.”
I’d be surprised if RFK used the Oxford Comma.
CSIS go take this research and get it developed for the world
