Water is “almost identical” to hydrogen peroxide.
Food and poop are both composed of atoms, so there’s essentially no difference between them.
I came here to talk about methyl groups and no one gives them a mention :(
I’m not a chemist but I like drugs. What’s up with methyl groups?
A methyl group is the name given to single carbon (with 3 hydrogens attached) when substituted onto a larger chemical moiety (a structure or motif in chemistry). When people speak about methyl groups they’re mostly speaking about those single carbon methyl group being attached to a heteroatom (atoms other than carbon and hydrogen in organic chemistry, like nitrogen, oxygen, sulfur, etc.).
Methamphetamine (N-methylamphetamine or N-methyl alpha-methyl-phenyl-ethylamine in full form) has a methyl group on it’s amine (nitrogen or N-position), which drastically alters its psychological effects and the way it’s synthesized by chemists (requiring methylamine). The methyl group there prolonges the stimulating effects, while also providing serotonergic effects (generally euphoric effects caused by interaction with the serotonin receptor transport protein), which gives it much greater addiction potential.
Methyl groups in general don’t “make drugs stronger” like the other guy said. To consider drug receptor interaction you need to take into account how well a molecule fits into the receptor you’re targetting as a whole.
Thats super interesring. It always amazes me how a small modification like a methyl group can so drastically alter the psychoactive properties of a substance. The body is such a nuanced and complicated system, its fascinating.
I really hope drug laws change so that we can see more research being done. Things like this help us learn more about not just the sustance, but the way our chemisty works & how our concious experience is shaped.
If you have any cool links on this topic, id love to browse them. Either way thanks for your run down on methyl groups :)
Removed by mod
While we are glad you used the trade mark your misspelling means we will have to dock part of your stipend.
John Soda Marketing Exec
What exactly is methanol a good example of? Are you saying methanol is a “stronger drug” than some other type of alcohol? Honestly confused here.
No idea what they’re on about, but if I had to wager a guess…
Ethyl alcohol, is generally drinking alcohol. You’ll find it in every bottle of liquor or spirits or beer… Also known as ethanol, it’s a good time. There are some studies linking it to cancer so please self regulate.
Methyl alcohol, aka methanol is most commonly associated to moonshine, though, commonalities shouldn’t necessarily imply that all moonshine or moonshine labeled or marketed products contain methanol. As an alcohol, it has a similar but usually a perceived stronger effect. The problem is that the bodies natural systems to break down methyl alcohol actually cause the body up convert it into two different neurotoxins, which is where moonshine gets the reputation that it makes you go blind. The neurotoxins literally cause nerve damage causing your vision to be lost in extreme cases. In very low doses, the likelihood of long term effects from drinking methanol is rather low, but large doses of methanol have the very real chance of blinding or killing you.
Due to this, I expect the poster was trying to make a joke about how methanol is significantly more potent than “regular” alcohol aka ethanol; implying it was stronger due to “meth”.
But I’m just guessing.
They both contain one methyl group, however. It’s literally the alcohol with the fewest methyl groups. I mean we could start talking about isopropyl alcohol with two, but I’d hesitate to characterize it as a “drug”.
It is a drug mate
Isopropyl alcohol? I guess in the sense that any poison is a drug. It’s not going to have any positive effects at any dose. I wouldn’t know how to quantify it’s “strength” vs methanol. LD50, assuming the desired effect was death?
Please go and drink some then, if this is really what you think.
I’m still waiting for someone to acknowledge my extremely lame pun in the title. It’s hard being this unfunny.
It made me think of Beth’s song from Dog the Bounty Hunter if that means anything. I finally realized its a Barnes and Barnes joke as well.
Here’s an article by a psychiatrist that goes into more detail.
This study asks abusers how much they use in an average day, and gets numbers from about 300 to 800 mg. An average clinical dose of either Adderall or Desoxyn would be about 20 mg a day.
It also talks about that meth acting more quickly (which can make it more addicting), and people injecting or snorting it (which makes it act more quickly).
Nice source/quote! Just to add my personal experience, when I was first put on modafinil (diphenylmethyl-sulfinylacetamide) for debilitating fatigue and brain fog, I asked my doctor if I’d experience a high or feel super focused. He explained that taking 200mg of modafinil would make an otherwise healthy person 20% more stimulated (for example). But there’s something wrong with me so I’m only functioning at 60% to begin with. When I take 200mg modafinil it also stimulates me by 20%, but that only brings me up to 90% of what a normal healthy person feels like anyway. So I don’t feel a high, I just feel closer to normal. That’s heavily paraphrased and really oversimplified, but it helped me understand it a bit better when I was young and worried about taking all these medications.
I mean, Methamphetamine is extremely similar, pharmacologically, with Adderall. Desoxyn is the ‘medicine brand name’ for meth, to treat ADHD.
Biggest difference between Crystal Meth, the street drug, and Desoxyn, the medicine, is dosage. A Desoxyn tablet is about 100x less methamphetamine than you’d take to ‘get high’. (not to mention, pills have a slower release than smoking it).
And yeah, there are other differences between Adderall and Meth; for the most part, Adderall is safer, less addictive, and less ‘makes you high’. So there’s very few people still using Desoxyn, but it is still out there. For reasons that aren’t really understood, Methamphetamine does work to treat a few people’s ADHD for whom Adderall doesn’t do much.
(and, for that matter, there are a pretty huge array of different amphetamines to treat ADHD and similar things, that are all subtly different in not very well understood ways, made messier by the fact that pharmaceutical companies making sure to push out a new drug, that might just be a new mix of existing drugs, every 10 years, for patent reasons. But Desoxyn is basically a ‘last resort’ to throw at the wall, if the patient hasn’t responded well to any of the others.)
I feel like the biggest difference by far is that most amphetamines are prescribed in XR formulations these days. The feeling caused by a slow trickle of product from a laser-drilled capsule or time-release beads over 8-12 hours is incomparable to the rush of smoking or snorting powdered amphetamine. For a lot of drugs the biggest addiction driver is actually the rise rate which causes the “hit”. i.e. compare addictive cigarettes with nearly harmless pipe.
That’s why when people abuse Adderall they usually crush it up and toot it, and they aren’t railing 100 tablets at a go.
Myself I have taken Adderall and now take Dexadrine (it’s cheaper) and have never felt any addictive pull from either. When I go camping I always take a multi-day break and never feel any ill effects other than a desire to chase squirrels and bother strangers with excessive chat.
I always bring some with me though so I can take one on the last day and effectively pack up my campsite without leaving anything behind, lol
I’m just putting this out there, that, cocaine also helps treat ADHD.
It’s not used in clinical treatments, but it has been observed that while neurotypical brains exposed to cocaine get an unfocused energy increase, ADHD brains tend to get a higher level of focus with that energy increase.
Theoretically it’s possible for someone to treat their own ADHD using cocaine.
… It’s a really bad idea, but it’s possible.
Ah yes, that’s what the methheads in my state are smoking, Adderall! Not methamphetamine (or are they, since they are the same thing now apparently?)
It’s so clear to me now, why wouldn’t you? Adderall is so much cheaper than methamphetamine and readily available!
Because a psychiatrist would prescribe the same amount that you would get on the streets. Such genius, Vice. Much heterodox.
I believe that’s what the kids would call, “ratioed”
“coffee is also a stimulant, like meth” Its a blatant attempt to get the hysteria boiling by a news company. Gotta get those clicks.
Garbage post, “redditor here!1!!” levels of cringe.
Are we seriously going to repost from facebook now?
Given the name/purpose of this community, I would say absolutely. The content of the conversation fits, so who cares the platform on which it happened? Lord knows I don’t want to spend my time looking at every post on Facebook to see stuff like this, that’s why we have aggregators.
Exactly. Except I’m a human, stealing content from Reddit to get this community started.
You don’t get it though, buddy here simply wants to complain about how their taste in content is superior instead of simply not following the community! Poor guy, leave them alone!
Just like on the original Reddit sub, reposts from any and all social media are permitted. It’s basically the point of this community. All posts on here to date have been reposted from Reddit, and about a third of those originated on Facebook. But a big thank you @DominicHillsun for the first homegrown OC - I’m the creator and mod of this community, as well as OP.
How very apropos of you, OP. It’s DYKWIA inception. 🧑🍳🤌🏼🤣
I wondered if I was a bit close to breaking my own “don’t be dick” rule, but I couldn’t resist!
There it is: rules for the but not for meeeee!
Mods can decide to be a dick, but we all should be civil all the time.
Do you think I came down on the wrong side of being a dick? I haven’t modded before, it’s just me, and it’s really hard to decide where to draw the line. I don’t want to be a hypocrite and I don’t want to be too heavy handed in removing comments or banning people if it comes to that.
My thought process here was this guy’s initial comment was dickish but not to the point where it required removing their comment. I felt it was unnecessarily rude, but I don’t have the thickest skin. My reply was completely accurate and not rude, but it was heavy on the sarcasm. My ruling: neither of us broke the rule. What’s your take on it?
I stickied a post to the top of this community inviting feedback and suggestions on how to mod this community and what the rules should be. I’m also looking for more people to mod this community with me. I’m actively encouraging input and feedback so please add your thoughts to the stickied post - I genuinely want more people than just me deciding what’s ok and what’s not.
The reply is dumb but the re-reply is cringe lol
